KMID : 0882420130840060851
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Korean Journal of Medicine 2013 Volume.84 No. 6 p.851 ~ p.854
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A Case of Dyspnea Caused by Local Botulinum Toxin Type A Injection
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So Hoon-Sub
Moon Min-Young Lee Jung-Su Kim Ho-Cheol Kang Byung-Chul Koh Youn-Suck
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Abstract
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Botulinum toxin type A is widely used for functional improvement of muscles and aesthetic plastic surgery. It paralyzes the injected muscle by inhibiting acetylcholine release from synapses of neuromuscular junctions. We herein report a case of progressive respiratory distress after botulinum toxin injection at both the gastrocnemius and soleus muscles. The patient also showed ptosis, dysphonia, dysphagia, and general weakness. Vocal cord dysfunction was observed by laryngoscopy. Other neurologic examination findings, including those of the physical examination, brain MRI, and Jolly¡¯s test, were normal. To our knowledge, this is the first report of botulinum toxin injection associated with dyspnea (MRC dyspnea scale, grade 3) in Korea.
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KEYWORD
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Botulinum toxin, Type A, Dyspnea
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